Biological Activity of Thiamine Anhydride Oxides. I
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چکیده
منابع مشابه
Oxidation Product of Thiamine Anhydride and the Metabolite of Thiamine Anhydride in Rats.
As shown in the previous paper, a metabolite of thiamine anhydride (TA) (I) was isolated as crystals melting at 172-173•‹ from the urine when TA was given parenterally to rats and it was assumed to be thiamine anhydride sulfoxide (TAO) (II) from its analytical data. It is known, however, that TA can be oxidized to TA sulfone (III) besides its sulfoxide by hydrogen peroxide according to the con ...
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The biosynthesis of thiamine appears to be accomplished with the initial formation of the pyrimidine and thiazole moieties by independent biosynthetic pathways, followed by a final step in which 2-methyl-4-amino-5-hydroxymethylpyrimidine and 4methyl-5-(/3-hydroxyethyl) thiazole are joined together to give thiamine. This conclusion was indicated originally from the observations that certain thia...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1959
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.79.1_115